As shown in Figure 2A–2H, the expression of SURF4 was highest in T4 (P = 0.014), infiltrating ductal carcinoma (P < 0.001), ER negative (P < 0.001), PR negative (P < 0.001), and HER2 positive (P < 0.001) patients. This evidence concerns the gene ESR1 and invasive ductal breast carcinoma.