EGFR and cancer: The expression of components of several cancer-related signaling pathways, such as Mammalian Target of Rapamycin (MTOR) [5, 6], PI3K/AKT [7, 8], Insulin-like Growth Factor-1 (IGF-1) [9] and Epidermal Growth Factor Receptor (EGFR) [10, 11] pathways are frequently disturbed in LUAD.