IFNGR1 and graft versus host disease: After reconditioning and the induction of GVHD [BALB/c→(Β6.Ifngr1–/–→B6.SJL]], we observed increased GVHD-induced mortality (Figure 2D) and enhanced expansion of infused donor BALB/c-Luc lymphocytes in recipient chimeric mice lacking the IFN-γR on host hematopoietic cells, as tested by BLI (Figure 2E).