In comparison with cancer control, EBPS caused a significant increase in COX-1 production (0.498 ± 0.02 μg Eq/mL, 32.80%) synchronous with a considerable decrease in COX-2 synthesis (0.143 ± 0.01 μg Eq/mL, 32.86%) in the protective group (P ≤ 0.05). Here, PTGS2 is linked to cancer.