Therefore, we investigated if the frequency of circulating or tumour-infiltrating CD45+ cells expressing ICs correlated with patient demographics or clinical features of the tumour, including treatment response, tumour stage and adverse features of the tumour, which have been shown to predict poor responses to current standards of care and survival in OAC patients in a study by Donlon et al. (2020), and include perineural invasion and lymphovascular invasion. This evidence concerns the gene PTPRC and neoplasm.