Finally, we found that both dendrimers increased E-Cadherin levels,apparently promoting an epithelial phenotype in both androgen sensitiveand resistant PCa cells, presumably hindering epithelial-mesenchymaltransition and thus reducing cancer cells’ invasion capacity.Furthermore, we observed that G2Ru and G2P significantlyreduced CD133 and ALDH1A1, respectively. This evidence concerns the gene PROM1 and posterior cortical atrophy.