A clear increase in the effectiveness of both CD4 and CD8 T cell control could be seen in the absence of pUL11, as indicated by a greater reduction in the virus spread in HCMV Merlin dUL11 GFP-infected cultures than in HCMV Merlin GFP infections in the presence of CD4 or CD8 T cells (Fig. 3B). Here, CD4 is linked to infection.