In addition, we looked into a native IDR-containing protein, EWS::FLI1, an oncogenic TF causing Ewing sarcoma (Grünewald et al., 2018) and known to form local high-concentration hubs at target genes associated with GGAA microsatellites (Chong et al., 2018). This evidence concerns the gene FLI1 and Ewing sarcoma.