Our study found that AP patients with complications, such as pseudocyst, acute respiratory failure, sepsis, infectious pancreatic necrosis, and acute renal failure had significantly increased inflammatory indicators, such as WBCs, neutrophils, CRP, and ESR, while RBCs, Hb decreased significantly, indicating that the pathological basis of AP complications is an inflammatory response, and malnutrition and ischemia and hypoxia may further aggravate this inflammatory response. The gene discussed is CRP; the disease is acute respiratory failure.