Interestingly, after introducing other confounding factors, we found that none of the factors representing acute inflammatory responses like WBCs, neutrophils, and CRP were independent predictors of pseudocysts, whereas ESR and PLTs were independent predictors, indicating that pancreatic pseudocyst is not caused by a simple acute inflammatory reaction, but is closely related to multiple complex factors, including chronic inflammation of pancreas. This evidence concerns the gene CRP and Pancreatic pseudocyst.