RAGE inhibitors like azeliragon and TTP488 prevent RAGE from interacting with many ligands, including AGEs, HMGB‐1, S100 protein, LPA, Mac‐1, and AβP, which are involved in the pathogenesis of SARS‐CoV‐2 infection, limiting pulmonary inflammation, and ALI/ARDS that are observed in Covid‐19.103, 104. Here, AGER is linked to COVID-19.