Elsewhere, SPTBN1 overexpression reduced the contents of MMP2, MMP9, IL‐8, IL‐1β, IL‐6, and Bcl2 but ascended the levels of Bax and cleaved caspase3 in RA‐FLSs, implying that SPTBN1 upregulation helped to repress the migration, inflammation and promoted the apoptosis of RA. Here, MMP9 is linked to rheumatoid arthritis.