In participants with the highest f‐Hb concentration just below cut‐off (>40‐46.9 μg Hb/g feces), 1.08% had an interval CRC detected at 24 months, as opposed to 0.06% in those with an unmeasurable f‐Hb concentration (Figure 4A). The gene discussed is GSTM1; the disease is colorectal carcinoma.