In participants with the highest f‐Hb concentration just below cut‐off (>40‐46.9 μg Hb/g feces), 0.83% had an interval CRC detected at 24 months, as opposed to 0.07% in participants with unmeasurable f‐Hb concentrations (Figure 4B). The gene discussed is GSTM1; the disease is colorectal carcinoma.