In the analysis of serum CRP level, 11 included literatures have statistical heterogeneity (P < 0.01) and were divided into “tumor surgery” subgroup and “nontumor surgery” subgroup according to the type of surgery; the former included 4 literatures and the latter included 7 literatures, resulting in P = 0.28 for heterogeneity between groups, while heterogeneity within the two subgroups remained significant, as shown in Figure 4. The gene discussed is CRP; the disease is neoplasm.