In rodent models of sepsis, metformin treatment showed improved survival, protection against acute respiratory distress syndrome (ARDS) and sepsis‐induced organ failure and prevention of sepsis‐associated immunosuppression, possibly related to AMP‐activated protein kinase activation and IL‐6 and IL − 1 inhibition.9, 10, 11, 12. The gene discussed is IL6; the disease is acute respiratory distress syndrome.