PODXL and neoplasm of testis: Cheung et al. [111] found that in testicular malignancies, hypermethylation of an intron region spanning miR-199a resulted in downregulation of its expression, which in turn led to abnormal upregulation of the expression of its target protein podocalyxin-like protein 1 (PODXL), affecting the aggressive behaviour of testicular tumours.