In cytogenetically normal AML (CN-AML) patients, lower ID3 and ID4 expression was nearly or markedly correlated with shorter OS (P = 0.027 and 0.034, respectively) and DFS (P = 0.037 and 0.056, respectively), whereas the other ID members did not affect either OS or DFS times (P > 0.05) (Fig. 2). This evidence concerns the gene ID4 and acute myeloid leukemia.