We thus examined the expression pattern of the 17 eGenes in two independent cohorts of 266 or 118 PCa patients71,72 and found that most of the eGenes indicated high degree of co-expression with HNF1B and ERG, and interestingly, FAM57A together with GEMIN4 and VPS53 at the 17p13.3 PCa risk locus consistently displayed the strongest co-expression with both HNF1B and ERG (Fig. 6e and Supplementary Fig. 10a). Here, HNF1B is linked to posterior cortical atrophy.