ERG and neoplasm: To validate the effect of the HNF1B cell cycle signature among a set of clinical variables to patient prognosis, we conducted multivariate analysis by incorporating clinical variables including age, Gleason score, PSA, tumor stage, ERG-fusion status, seminal vesical status and extraprostatic extension status in PCa patients using both the continuous and categorical HNF1B cell cycle signature by the median stratification.