TMPRSS2 and posterior cortical atrophy: When taking into account of TMPRSS2-ERG fusion status and stratifying patients into TMPRSS2-ERG fusion-positive and negative groups, we observed that the eQTL results from the ERG fusion-negative group are non-significant (Fig. 3m and Supplementary Fig. 4), whereas seven SNPs showed significant eQTL signal with HNF1B in the TMPRSS2-ERG fusion-positive PCa tumors (Fig. 3n and Supplementary Fig. 5a–n).