In both TNBC patient 4 and 9, CD138 has significantly polarized away the tumor-immune boundary (p = 5.12 ×  10−27 in patient 4 and p = 7.17 × 10−52 in patient 9, two-sided Wilcoxon rank sum test, Fig. 5i top right and bottom right). This evidence concerns the gene SDC1 and neoplasm.