Besides these routine laboratory parameters, the related evidence indicated that the emerging laboratory parameters such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and a recently described prognostic marker C-reactive protein (CRP)/lymphocyte ratio (CLR) have been considered useful indicators for diagnosis and prognosis of various infectious and inflammatory diseases, including cancers, autoimmune disease as well as COVID-19. Here, CRP is linked to autoimmune disease.