The patients with infections had more clonal B‐cells (median 28.4 vs. 13.32 × 109/L, p = 0.043), a higher relative number of clonal B‐cells (median 93.3% vs. 81.5%, p = 0.046), a smaller proportion of polyclonal B‐cells (median 0.14 vs. 0.24%, p = 0.041), NK cells (median 1.48 vs. 3.1%, p = 0.049), and CD4+ cells (median 3.2 vs. 9.29%, p = 0.033). Here, CD4 is linked to infection.