STMN1, SMARCC1, ALDOA, CLTC, PSMG1, SUZ12, DAG1, PGRMC1, and HMGCR, and MYO10 were upregulated following compound treatment Additionally, the compounds against Alzheimer’s disease were identified and their BBB permeability levels were predicted. Here, PSMG1 is linked to Alzheimer disease.