Interestingly, we found that the expression of PYCRL, LOC100133130, MELK, LINC01101, and DLG3-AS1 was downregulated, and the expression of RPL3L, PLEK2, and CD99P1 was upregulated in PD patients compared with the healthy samples (Figure 6A). The gene discussed is PLEK2; the disease is Parkinson disease.