In this study, based on the non-coding RNA and gene expression data of human islet exosome, we constructed networks combined with the regulatory associations of candidate lncRNA-miRNA and miRNA-mRNA, lncRNA-related ceRNA analysis networks.Our data revealed potential markers of type 1 diabetes, including lncRNA PVT1, LINC00960, hsa-miR-107 and elucidated the mechanisms they may involved in. Here, PVT1 is linked to type 1 diabetes mellitus.