The base model of all-cause mortality (AUC:0.667) included COPD, CKD, NYHA, systolic BP, diastolic BP, ALT, AST, uric acid, sodium, potassium, lg NT-proBNP, and LVEF, while the base model of cardiovascular mortality (AUC:0.733) included hypertension, CKD, NYHA, systolic BP, diastolic BP, ALT, AST, uric acid, sodium, potassium, lg NT-proBNP, and LVEF. The gene discussed is NPPB; the disease is chronic obstructive pulmonary disease.