Limited clinical studies have demonstrated expressions of target lncRNAs in peripheral blood of CVS patients and linked their levels to clinical features of the disease as follows; a) For NEAT1, previous two studies have demonstrated increased NEAT1 in stroke patients compared to controls and not related to clinical categorical variables including hypertension but they found a positive correlation between NEAT1 level and NIHSS score [6,34]. This evidence concerns the gene NEAT1 and Stroke.