BMAL1 and hepatocellular carcinoma: Consistent with the data from HCC tissues, BMAL1 expression was also remarkably lower in eight HCC cell lines (HLE, HLF, Hep3B, SNU-368, SNU-398, SNU-739, Huh7 and MHCC97H) compared with that in normal hepatocyte THLE-2 (Figure 1F and 1G).