BMAL1 and hepatocellular carcinoma: Furthermore, both univariate and multivariate Cox analysis revealed an association between higher BMAL1 expression and favorable survival outcomes, including OS (univariate HR: 0.544, 95% CI: 0.375-0.790; multivariate HR: 0.598, 95% CI: 0.403-0.889) and RFS (univariate HR: 0.504, 95% CI: 0.361-0.705; multivariate HR: 0.511, 95% CI: 0.358-0.731) in patients with HCC (supplementary Table 4-7).