In addition, infection by SARS-CoV-2 increases glycolytic activity and the expression of inflammatory genes such as TNF-α, IL-6, IL-1β, INF-α and INF-β (Andrade Silva et al., 2021), and this inflammatory response is potentially harmful to renal tissue (de Rivero Vaccari et al., 2020). The gene discussed is IL1B; the disease is infection.