TLR7 and nephritis: In our work, all genotypes and alleles TLR7-rs3853839 were associated with nephritis (CC vs CG P < 0.0001, OR 0.13, 95% CI 0.05–0.35/CC vs GG = 0.04, OR 0.10, 95% CI 0.01–0.87/CC vs CG + GG, P < 0.0001, OR 0.12, 95% CI 0.05–0.32/C vs G P = 0.0001, OR 0.21, 95% CI 0.10–0.47).