Moreover, it is known that Bax may oligomerize and trigger mitochondria-dependent apoptosis, however, we observed an elevation of the only Bax monomer, while Bax dimer was downregulated compared with the T2DM group, that may explain the absence of the signs of apoptosis and mitoptosis during the electron microscopy examinations. The gene discussed is BAX; the disease is type 2 diabetes mellitus.