CDK5 and fibrosarcoma: investigated the cyclin-dependent kinase 5 (Cdk5)/Talin 1 (Tln1)/focal adhesion kinase (FAK) axis in breast cancer and fibrosarcoma extravasation using a three-gel channel microfluidic device, where the microvasculature was in the center and stromal cells are seeded in the left and right gel channels (27).