Analysis of the cBioPortal and TCGA databases showed increased frequencies of SKA1–3 mRNA expression in HCC of 4%, 11%, and 9%, respectively (Figures 3 and 5), with AUC values of 0.982, 0.887, and 0.973, respectively (p < 0.05; Figure 4). Here, SKA1 is linked to hepatocellular carcinoma.