TOP2A and hepatocellular carcinoma: The elevated expression of CDK1, CCNB1, CCNA2, TOP2A, BUB1, AURKB, CCNB2, BUB1B, NCAPG, and KIF11 was observed by TCGA analysis in HCC (p < 0.05), and these elevated expressions were significantly connected to the disease-free progression and OS of HCC patients (27).