CEACAM5 and Pleural effusion: Zhang X used four routinely detected variables, namely carcinoembryonic antigen (CEA) levels, monocyte counts, N-terminal parent-B natriuretic peptide (NT-pro-BNP) levels, and pleural effusion chloride levels at admission as predictors and developed the CONCH prognostic scoring system, which can guide the choice of malignant pleural effusion (MPE) interventions and management (26).