Upregulation of Kinetochore Metaphase Signaling, and Polyamine Regulation in Colon Cancer Pathways; and CENPA, DNAH1, H2AX, KNL1, RAD21, STAG3, ZWILCH, ZWINT, AKT1 and 3, ARAF, and MYC genes. Here, H2AX is linked to malignant colon neoplasm.