In the right-sided colon tumors, PKHD1 co-occurred with ARID1B, ARID2, B2M, CTCF, FAT1, FLT1, FLT3, and PDE11A, most of which were DNA damage genes, whereas KRAS was found mutually exclusive with ARID1B (Figure 4D). Here, KRAS is linked to digestive system cancer.