For example, transplantation of CD90low MSCs derived from mouse compact bone into a mouse model of ovarian cancer promotes the expression of interleukin-12 (IL-12), interleukin-21 (IL-21), interferon-γ (IFN-γ), and the pro-inflammatory factor chemokine (C-X-C motif) ligand 10 (CXCL10), and inhibited the expression of anti-inflammatory factors, including interleukin-10 (IL-10) and C-C chemokine ligand-5 (CCL-5), thereby suppressing tumor growth and improving survival (9). This evidence concerns the gene IL21 and neoplasm.