Furthermore, VISTA expression was found to be positively correlated with PD-1 expression on CD3+ T cells (rs = 0.362, P = 0.030), and there was a positive correlation with Tim-3 on CD3+ T cells (rs = 0.428, P = 0.009) and CD8+ T cells (rs = 0.636, P < 0.001) as well as a positive correlation with TIGIT on CD4+ T cells (rs = 0.336, P = 0.045) and Tregs (rs = 0.386 P = 0.020) (Figures 2D, 3B) in BM from MM patients. The gene discussed is TIGIT; the disease is Miyoshi myopathy.