TIGIT and Miyoshi myopathy: Interestingly, a higher frequency of VISTA and its co-expression with PD-1, Tim-3, and TIGIT was observed in PB in MM compared with HIs (VISTA+ T cells: median: 8.68 vs 3.78, P < 0.001; VISTA+PD-1+ T cells: median: 1.67 vs 0.46, P < 0.001; VISTA+Tim-3+ T cells: median: 0.41 vs 0.27, P = 0.008; VISTA+TIGIT+ T cells: median: 5.97 vs 2.19, P < 0.001) (Figure 2C).