In addition, immunohistochemistry (IHC) showed positive staining for CD34 and heterogeneous retinoblastoma deficiency, and fluorescence <i>in situ</i> hybridization (FISH) showed no amplification of mouse double minute 2 homolog and no rearrangement of <i>FUS</i> or <i>EWSR1</i>. The gene discussed is EWSR1; the disease is retinoblastoma.