Notably, in some cases oncogenic activity of AJUBA has been correlated with increased YAP activity (Bi et al., 2018; Li et al., 2019; Zhang et al., 2018), whereas tumor suppressor activity of AJUBA has been correlated with decreased YAP activity (Gao et al., 2014; Liu et al., 2018; Tanaka et al., 2015). Here, AJUBA is linked to neoplasm.