Compared with SHAM + Scr siRNA rats, HF + Scr siRNA rats had higher protein levels of p-NF-κB p65 (Figure 4A), lower protein levels of IκB-α (Figure 4B), and higher protein levels of p-ERK1/2 (Figure 4C) in PVN. This evidence concerns the gene NFKB1 and hydrops fetalis.