It has indeed been shown in the radiation-resistant triple negative breast cancer cell line (MDA-MB-231-IR) that membrane binding of the natural phenolic lipid 10-gingerol modulates lipid domain, affecting the PI3K/Akt signaling pathway and thereby inhibiting cancer cell proliferation, migration and invasion while inducing apoptosis (Ediriweera et al., 2020). The gene discussed is AKT1; the disease is cancer.