Gastrodia elata Blume (GE) is a traditional Chinese herbal medicine with anti-inflammatory activity, and according to a study, GE significantly decreased the IL-6, CXCL8, MMP-3 and MMP-13 levels in TNF-induced rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). The gene discussed is MMP3; the disease is rheumatoid arthritis.