AKT1 and ovarian cancer: MiR-497 targets vascular endothelial growth factor A through PI3K/AKT and MAPK/ERK pathways to inhibit ovarian cancer angiogenesis (46) Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the psat1-dependent GSK3β/β-catenin signaling pathway (47).