Increased baseline levels of peptidoglycan recognition protein-1 (PGLYRP-1), a pro-inflammatory molecule that binds peptidoglycan, were independently associated with an increased risk of first atherosclerotic cardiovascular disease (ASCVD) in a ten-year cohort, suggesting that PGLYRP-1 may contribute to the development of ASCVD (58). Here, PGLYRP1 is linked to atherosclerosis.