Alopecia-like phenotypes have also been noted in other mutant strains with aberrant SG formation or sebum production, including mice lacking key sebaceous proteins such as FA 2-hydroxylase (Fa2h), diacylglycerol-O-acyltransferase 1 (Dgat1), cell death-inducing DFFA-like effector A (Cidea), ceramide synthase 4 (CerS4), gasdermin A3 (Gsdma3) and others (266–273). The gene discussed is CERS4; the disease is alopecia.