The discrepancy between these two findings could be attributed to the study design and sample size difference, which was a prospective cohort with iron supplement intervention and 141participant (73 SCD patients and 68 non‐SCD patients), respectively in the case of Gomez et al.37Nonetheless, Fiorelli42 in an editorial explained that the positive correlation between serum ferritin levels and MCV and MCH levels may reflect increased iron uptake and hemoglobin synthesis by immature erythroid cells. The gene discussed is PMCH; the disease is Schnyder corneal dystrophy.