CD4 and Alzheimer disease: Compared with control, AD hippocampus demonstrated decreased memory B cells (0.1005±0.06696 vs 0.1463±0.0961, P = 0.0049), increased memory resting CD4+ T cells (0.1166±0.1111 vs 0.0720±0.0961, P = 0.0123), increased memory activated CD4+ T cells (0.016483 ± 0.034499 vs 0.010017 ± 0.029136, P = 0.0227), and increased resting NK cells (0.0423 ± 0.0501 vs 0.0347 ± 0.029136, P = 0.0099).