In investigated COVID-19 patients, MMP-8 displayed a strong positive correlation with TGF-β and negative correlation with rations IL-10/IL-6, IL-10/IL-17, and IL-10/TNF-α, thus suggesting predomination of anti-inflammatory cytokines and complementing the pro-inflammatory effects of MMP-9 and IL-6 37. The gene discussed is MMP8; the disease is COVID-19.