We found six downregulated lncRNAs (C12orf77, TCL6, C8orf49, PCGEM1, and ERVMER61-1), and two upregulated lncRNAs (HOTTIP and LINC00200) were significantly related to the progression of ccRCC. The gene discussed is PCGEM1; the disease is nonpapillary renal cell carcinoma.