From the clustering of references, reference bursts, frequent keywords, keyword clustering, and keyword hotspot changes, it can be seen that pharmacokinetics; the mechanism of action of diazepam (GABA/GABAR, gephyrin, astrocytes, and oxidative stress); its application in disease (especially in status epilepticus, intranasal use, and febrile seizures); and the risk, testing, and management of diazepam are the four directions of research focus and future development. The gene discussed is GPHN; the disease is status epilepticus.