AGT and type 1 diabetes mellitus: Our results are consistent with previous reports of the EP4 receptor playing a key role in a variety of disease models associated with increased inflammation, including type 1 diabetes (Rahman et al., 2018), endometritis (Li et al., 2019), angiotensin II-induced abdominal aortic aneurysm (Hiromi et al., 2020), airway inflammation (van Geffen et al., 2021), and nephrotoxic serum nephritis (Aringer et al., 2018).